Management of Soft Tissue Sarcoma

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Others are malignant cancer and are called soft tissue sarcomas. There are more than 30 types of sarcoma, making each extremely rare. Sarcomas are classified into groups that have similar types of cancer cells and symptoms. They usually are named for the type of tissue where they start. Sarcomas within a classification often are treated the same way. Anything that increases your chance of getting cancer is a risk factor.

For sarcoma, risk factors include:.

General Information About Adult Soft Tissue Sarcoma

Not everyone with risk factors gets sarcoma. Some cases of soft tissue sarcoma can be passed down from one generation to the next. Genetic counseling may be right for you. Signs of sarcoma vary from person to person. Many times sarcoma does not have symptoms in the early stages.

Only about half of soft-tissue sarcomas are found in the early stages before they spread. These symptoms do not always mean you have sarcoma. However, it is important to discuss any symptoms with your doctor, since they may also signal other health problems. In fact, we are one of the few centers in the world with specialized doctors who focus on diagnosing only sarcomas. We have the latest methods and technology to be sure you get the most accurate diagnosis possible.

This can make a difference in the success of your treatment. Since sarcomas are complex and can develop in so many places in the body, they can be difficult to diagnose. Getting the wrong diagnosis may actually be harmful and make therapy have less chance for success. A biopsy that is not done correctly can cause the cancer to spread and make your treatment more difficult.

It is best for the surgeon who does the biopsy to also remove the tumor. If at all possible, your first biopsy should be at the cancer center where you will receive treatment. Try to go to a cancer center that sees a large number of sarcoma patients and has a specialized sarcoma team that includes specialized pathologists. If you have symptoms that may signal sarcoma, your doctor will examine you and ask you questions about your health and your family medical history.

We welcome the opportunity to provide second opinions sarcomas. The only way to be certain a tumor is sarcoma is a biopsy removing a small number of cells to examine under a microscope. Imaging tests may be used before or after biopsy to determine the location and extent of the tumor. CT computed tomography scans may be used to help guide the needle. Doctors trained to read these types of biopsies then review the small numbers of cells that are drawn into the needle.

If the test shows that the tumor may be a sarcoma, another type of biopsy probably will be done to remove a larger piece of tissue. If you are diagnosed with sarcoma, your doctor will determine the stage or extent of the disease. In soft tissue sarcomas, an additional factor, called grade G , is part of tumor stage. The grade is based on how the sarcoma cells look under the microscope. The official staging system divides sarcomas into three grades 1 to 3. The grade of a sarcoma helps predict how rapidly it will grow and spread, as well as your outlook for successful treatment prognosis.

The grade is part of what is used to determine the stage of a sarcoma.

Advances in Therapy for Sarcomas & GIST

The grade of a sarcoma is based on the way the cancer looks under the microscope. In grading a cancer, the pathologist considers three factors:. These factors are scored, and then the scores are added together to determine the grade of the tumor. The sarcomas with cells looking more normal and with fewer cells dividing are generally placed in a low-grade category.

Expected Benefits

Low-grade tumors are slow growing, slower to spread and often have a better outlook prognosis than higher-grade tumors. The grade is usually based on the way the cells look and how many are dividing, but certain types of sarcoma are automatically given higher scores for differentiation. This affects the overall score so much that they are never considered to be low grade. Examples of these include synovial sarcoma and embryonal sarcoma.

UK guidelines for the management of soft tissue sarcomas | Clinical Sarcoma Research | Full Text

The scores for each factor are added up to determine the grade for the cancer. Higher-grade cancers tend to grow and spread faster than lower-grade cancers. To assign a stage, information about the tumor, its grade, lymph nodes, and metastasis is combined by a process called stage grouping. The stage is useful in selecting treatment, but other factors, like where the sarcoma is located, also impact treatment planning and outlook.

Adult Soft Tissue Sarcoma Treatment (PDQ®)–Patient Version

Staging is a way of determining how much disease is in the body and where it has spread. This information is important because it helps your doctor determine the best type of treatment for you and the outlook for your recovery prognosis. Once the staging classification is determined, the stage stays the same even if treatment is successful or the cancer spreads. Your sarcoma treatment is customized specifically for you by one of the worlds' foremost teams of experts.

Because sarcoma is rare, most oncologists treat few if any patients in their careers. Statistics show that sarcoma patients have better outcomes when they are treated at large comprehensive cancer centers where specialized oncologists have more experience with the disease. Our surgeons are among the most skilled in the world in surgery for sarcoma.

They use the latest techniques, including limb-sparing surgeries, which we helped pioneer. Usually patients are able to avoid the loss of an arm or leg. We're making great strides in treating sarcomas. We helped developed concurrent chemo and radiation regimens to improve chance of successful treatment in certain types of sarcoma.

Sarcomas usually are treated with a combination of therapies that may include surgery, chemotherapy and radiation. If you are diagnosed with sarcoma, your doctor will discuss the best options to treat it. This depends on several factors, including:. Your treatment for sarcoma will be customized to your particular needs. It may include one or more of the following. They among the few surgeons in the world who specialize in sarcoma treatment, and they use the least-invasive and most-advanced techniques. Surgery is the main treatment for soft-tissue sarcomas.

Management of Soft Tissue Sarcoma

The surgeon removes the tumor, as well as a margin of healthy tissue around it to take out as many cancer cells as possible. You may receive chemotherapy or radiation therapy before or after the surgery. Because of a special type of surgery called limb-sparing surgery, which often is followed with radiation therapy, most patients do not have to have arms or legs removed to treat sarcoma. Chemotherapy may be used as the main treatment for sarcoma or with surgery or radiation. A combination of two or more chemotherapy drugs may be used.